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Mice develop normally without the H1(0) linker histone.

H1 histones bind to the linker DNA between nucleosome core particles and facilitate the folding of chromatin into a 30-nm fiber. Mice contain at least seven nonallelic subtypes of H1, including the somatic variants H1a through H1e, the testis-specific variant H1t, and the replacement linker histone...

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Bibliografiska uppgifter
Huvudupphovsmän: Sirotkin, A M, Edelmann, W, Cheng, G, Klein-Szanto, A, Kucherlapati, R, Skoultchi, A I
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1995
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC41532/
https://ncbi.nlm.nih.gov/pubmed/7604008
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