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Gene transfer of the Na(+),K(+)-ATPase β1 subunit using electroporation increases lung liquid clearance in rats

The development of non-viral methods for efficient gene transfer to the lung is highly desired for the treatment of a number of pulmonary diseases. We have developed a non-invasive procedure using electroporation to transfer genes to the lungs of rats. Purified plasmid (100 to 600 μg) was delivered...

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Main Authors: Machado-Aranda, David, Adir, Yochai, Young, Jennifer L., Briva, A., Budinger, G. R. Scott, Yeldandi, Anjana V., Sznajder, Jacob I., Dean, David A.
Formato: Artigo
Idioma:Inglês
Publicado: 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152914/
https://ncbi.nlm.nih.gov/pubmed/15516538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200403-313OC
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