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The Novel α(7)β(2)-Nicotinic Acetylcholine Receptor Subtype Is Expressed in Mouse and Human Basal Forebrain: Biochemical and Pharmacological Characterization

We examined α(7)β(2)-nicotinic acetylcholine receptor (α(7)β(2)-nAChR) expression in mammalian brain and compared pharmacological profiles of homomeric α(7)-nAChRs and α(7)β(2)-nAChRs. α-Bungarotoxin affinity purification or immunoprecipitation with anti-α(7) subunit antibodies (Abs) was used to iso...

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Detalhes bibliográficos
Main Authors: Moretti, Milena, Zoli, Michele, George, Andrew A., Lukas, Ronald J., Pistillo, Francesco, Maskos, Uwe, Whiteaker, Paul, Gotti, Cecilia
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152907/
https://ncbi.nlm.nih.gov/pubmed/25002271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.114.093377
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