IGFBP-3 mediates p53-induced apoptosis during serum starvation

Insulin-like growth factor binding protein (IGFBP)-3, a p53-response gene, can induce apoptosis in an IGF-independent manner. Here we demonstrate that IGFBP-3 mediates p53-induced apoptosis during serum starvation using two foil neoplastic cell models: one which introduces p53 activity and one which...

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Hlavní autoři: Grimberg, Adda, Liu, Bingrong, Bannerman, Peter, El-Deiry, Wafik S., Cohen, Pinchas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2002
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152903/
https://ncbi.nlm.nih.gov/pubmed/12118329
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