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Gambierol Inhibition of Voltage-Gated Potassium Channels Augments Spontaneous Ca(2+) Oscillations in Cerebrocortical Neurons

Gambierol is a marine polycyclic ether toxin produced by the marine dinoflagellate Gambierdiscus toxicus and is a member of the ciguatoxin toxin family. Gambierol has been demonstrated to be either a low-efficacy partial agonist/antagonist of voltage-gated sodium channels or a potent blocker of volt...

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Detalhes bibliográficos
Main Authors: Cao, Zhengyu, Cui, Yanjun, Busse, Eric, Mehrotra, Suneet, Rainier, Jon D., Murray, Thomas F.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152883/
https://ncbi.nlm.nih.gov/pubmed/24957609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.215319
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