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Gambierol Inhibition of Voltage-Gated Potassium Channels Augments Spontaneous Ca(2+) Oscillations in Cerebrocortical Neurons
Gambierol is a marine polycyclic ether toxin produced by the marine dinoflagellate Gambierdiscus toxicus and is a member of the ciguatoxin toxin family. Gambierol has been demonstrated to be either a low-efficacy partial agonist/antagonist of voltage-gated sodium channels or a potent blocker of volt...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Pharmacology and Experimental Therapeutics
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4152883/ https://ncbi.nlm.nih.gov/pubmed/24957609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.215319 |
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