Clinically Relevant Doses of Candesartan Inhibit Growth of Prostate Tumor Xenografts In Vivo through Modulation of Tumor Angiogenesis

Angiotensin II receptor type 1 blockers (ARBs), widely used antihypertensive drugs, have also been investigated for their anticancer effects. The effect of ARBs on prostate cancer in experimental models compared with meta-analysis data from clinical trials is conflicting. Whereas this discrepancy mi...

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Hlavní autoři: Alhusban, Ahmed, Al-Azayzih, Ahmad, Goc, Anna, Gao, Fei, Fagan, Susan C., Somanath, Payaningal R.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2014
Témata:
Drug Discovery and Translational Medicine
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152877/
https://ncbi.nlm.nih.gov/pubmed/24990940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.114.216382
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