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Corticosteroids modulate Seoul virus infection, regulatory T cell responses, and MMP-9 expression in male, but not female, Norway rats
Human hantaviral disease is mediated by excessive proinflammatory and CD8+ T cell responses, which can be alleviated by administration of corticosteroids. In contrast to humans, male rats that are infected with their species-specific hantavirus, Seoul virus (SEOV), have reduced proinflammatory and e...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4152707/ https://ncbi.nlm.nih.gov/pubmed/18931068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.2008/03715-0 |
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