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Corticosteroids modulate Seoul virus infection, regulatory T cell responses, and MMP-9 expression in male, but not female, Norway rats

Human hantaviral disease is mediated by excessive proinflammatory and CD8+ T cell responses, which can be alleviated by administration of corticosteroids. In contrast to humans, male rats that are infected with their species-specific hantavirus, Seoul virus (SEOV), have reduced proinflammatory and e...

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Detalhes bibliográficos
Main Authors: Easterbrook, Judith D., Klein, Sabra L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152707/
https://ncbi.nlm.nih.gov/pubmed/18931068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.2008/03715-0
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