Myeloid Kruppel-like Factor 2 deficiency exacerbates neurological dysfunction and neuroinflammation in a murine model of multiple sclerosis

Cells of the innate immune system are important mediators of multiple sclerosis (MS). We have previously identified Kruppel-like Factor 2 (KLF2) as a critical negative regulator of myeloid activation in the setting of bacterial infection and sepsis, but the role of myeloid KLF2 in MS has not been in...

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Main Authors: Shi, Hong, Sheng, Baiyang, Zhang, Chao, Nayak, Lalitha, Lin, Zhiyong, Jain, Mukesh K., Atkins, G. Brandon
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152407/
https://ncbi.nlm.nih.gov/pubmed/25052583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2014.06.023
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