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Do lamin B1 and lamin B2 have redundant functions?

Lamins B1 and B2 have a high degree of sequence similarity and are widely expressed from the earliest stages of development. Studies of Lmnb1 and Lmnb2 knockout mice revealed that both of the B-type lamins are crucial for neuronal migration in the developing brain. These observations naturally posed...

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Autores principales: Lee, John M, Jung, Hea-Jin, Fong, Loren G, Young, Stephen G
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152341/
https://ncbi.nlm.nih.gov/pubmed/25482116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.29615
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