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The value of regenotyping older linkage data sets with denser marker panels

OBJECTIVES: Linkage analysis can help determine regions of interest in whole genome sequence studies. However, many linkage studies rely on older microsatellite (MSAT) panels. We set out to determine whether results would change if we regenotyped families using a dense map of SNPs. METHODS: We selec...

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Main Authors: Vieland, Veronica J., Walters, Kimberly A., Azaro, Marco, Brzustowicz, Linda M., Lehner, Thomas
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151881/
https://ncbi.nlm.nih.gov/pubmed/24969307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000360003
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