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The value of regenotyping older linkage data sets with denser marker panels

OBJECTIVES: Linkage analysis can help determine regions of interest in whole genome sequence studies. However, many linkage studies rely on older microsatellite (MSAT) panels. We set out to determine whether results would change if we regenotyped families using a dense map of SNPs. METHODS: We selec...

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Détails bibliographiques
Auteurs principaux: Vieland, Veronica J., Walters, Kimberly A., Azaro, Marco, Brzustowicz, Linda M., Lehner, Thomas
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151881/
https://ncbi.nlm.nih.gov/pubmed/24969307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000360003
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