Inhibition of Hydrogen Sulfide Production by Gene Silencing Attenuates Inflammatory Activity by Downregulation of NF-κB and MAP Kinase Activity in LPS-Activated RAW 264.7 Cells

Hydrogen sulfide is an endogenous inflammatory mediator produced by the activity of cystathionine γ-lyase (CSE) in macrophages. The objective of this study was to explore the mechanism by which hydrogen sulfide acts as an inflammatory mediator in lipopolysaccharide- (LPS-) induced macrophages. In th...

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Hlavní autoři: Badiei, Alireza, Muniraj, Nethaji, Chambers, Stephen, Bhatia, Madhav
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151860/
https://ncbi.nlm.nih.gov/pubmed/25215294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/848570
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