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Inhibition of Hydrogen Sulfide Production by Gene Silencing Attenuates Inflammatory Activity by Downregulation of NF-κB and MAP Kinase Activity in LPS-Activated RAW 264.7 Cells

Hydrogen sulfide is an endogenous inflammatory mediator produced by the activity of cystathionine γ-lyase (CSE) in macrophages. The objective of this study was to explore the mechanism by which hydrogen sulfide acts as an inflammatory mediator in lipopolysaccharide- (LPS-) induced macrophages. In th...

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Autors principals: Alireza Badiei, Nethaji Muniraj, Stephen Chambers, Madhav Bhatia
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Limited 2014-01-01
Col·lecció:BioMed Research International
Accés en línia:http://dx.doi.org/10.1155/2014/848570
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