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Inhibition of Hydrogen Sulfide Production by Gene Silencing Attenuates Inflammatory Activity by Downregulation of NF-κB and MAP Kinase Activity in LPS-Activated RAW 264.7 Cells
Hydrogen sulfide is an endogenous inflammatory mediator produced by the activity of cystathionine γ-lyase (CSE) in macrophages. The objective of this study was to explore the mechanism by which hydrogen sulfide acts as an inflammatory mediator in lipopolysaccharide- (LPS-) induced macrophages. In th...
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Autors principals: | , , , |
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Format: | Artigo |
Idioma: | Inglês |
Publicat: |
Hindawi Limited
2014-01-01
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Col·lecció: | BioMed Research International |
Accés en línia: | http://dx.doi.org/10.1155/2014/848570 |
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