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Preclinical antitumor activity of SST0116CL1: A novel heat shock protein 90 inhibitor
4-Amino substituted resorcino-isoxazole (SST0116CL1) (property of Sigma-Tau Research Switzerland S.A.) is a potent, second generation, small-molecule heat shock protein 90 inhibitor (Hsp90i). SST0116CL1 binds to the ATP binding pocket of Hsp90, and interferes with Hsp90 chaperone function thus resul...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
D.A. Spandidos
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151799/ https://ncbi.nlm.nih.gov/pubmed/25096516 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2014.2575 |
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