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Mapping the λ Integrase bridges in the nucleoprotein Holliday junction intermediates of viral integrative and excisive recombination

The site-specific recombinase encoded by bacteriophage λ [λ Integrase (Int)] is responsible for integrating and excising the viral chromosome into and out of the chromosome of its Escherichia coli host. In contrast to the other well-studied and highly exploited tyrosine recombinase family members, s...

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Main Authors: Tong, Wenjun, Warren, David, Seah, Nicole E., Laxmikanthan, Gurunathan, Van Duyne, Gregory D., Landy, Arthur
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151763/
https://ncbi.nlm.nih.gov/pubmed/25114247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413007111
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