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Mutations in the amino-terminal domain of λ-integrase have differential effects on integrative and excisive recombination

Lambda integrase (Int) forms higher-order protein–DNA complexes necessary for site-specific recombination. The carboxy-terminal domain of Int (75–356) is responsible for catalysis at specific core-type binding sites whereas the amino-terminal domain (1–70) is responsible for cooperative arm-type DNA...

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Hlavní autoři: Warren, David, Lee, Sang Yeol, Landy, Arthur
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1808434/
https://ncbi.nlm.nih.gov/pubmed/15686557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2004.04447.x
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