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Mutations in the amino-terminal domain of λ-integrase have differential effects on integrative and excisive recombination
Lambda integrase (Int) forms higher-order protein–DNA complexes necessary for site-specific recombination. The carboxy-terminal domain of Int (75–356) is responsible for catalysis at specific core-type binding sites whereas the amino-terminal domain (1–70) is responsible for cooperative arm-type DNA...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1808434/ https://ncbi.nlm.nih.gov/pubmed/15686557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2004.04447.x |
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