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Two structural features of λ integrase that are critical for DNA cleavage by multimers but not by monomers

Despite many years of genetic and biochemical studies on the λ integrase (Int) recombination system, it is still not known whether the Int protein is competent for DNA cleavage as a monomer. We have addressed this question, as part of a larger study of Int functions critical for the formation of hig...

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Detalhes bibliográficos
Main Authors: Lee, Sang Yeol, Aihara, Hideki, Ellenberger, Tom, Landy, Arthur
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC365695/
https://ncbi.nlm.nih.gov/pubmed/14976241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400135101
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