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Nicotinic and muscarinic agonists and acetylcholinesterase inhibitors stimulate a common pathway to enhance GluN2B-NMDAR responses

Nicotinic and muscarinic ACh receptor agonists and acetylcholinesterase inhibitors (AChEIs) can enhance cognitive function. However, it is unknown whether a common signaling pathway is involved in the effect. Here, we show that in vivo administration of nicotine, AChEIs, and an m1 muscarinic (m1) ag...

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Detalhes bibliográficos
Main Authors: Ishibashi, Masaru, Yamazaki, Yoshihiko, Miledi, Ricardo, Sumikawa, Katumi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151735/
https://ncbi.nlm.nih.gov/pubmed/25114227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1408805111
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