MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma

Glioblastomas (GBMs) diffusely infiltrate the brain, making complete removal by surgical resection impossible. The mixture of neoplastic and nonneoplastic cells that remain after surgery form the biological context for adjuvant therapeutic intervention and recurrence. We performed RNA-sequencing (RN...

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Autori principali: Gill, Brian J., Pisapia, David J., Malone, Hani R., Goldstein, Hannah, Lei, Liang, Sonabend, Adam, Yun, Jonathan, Samanamud, Jorge, Sims, Jennifer S., Banu, Matei, Dovas, Athanassios, Teich, Andrew F., Sheth, Sameer A., McKhann, Guy M., Sisti, Michael B., Bruce, Jeffrey N., Sims, Peter A., Canoll, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2014
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151734/
https://ncbi.nlm.nih.gov/pubmed/25114226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405839111
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