MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma

Glioblastomas (GBMs) diffusely infiltrate the brain, making complete removal by surgical resection impossible. The mixture of neoplastic and nonneoplastic cells that remain after surgery form the biological context for adjuvant therapeutic intervention and recurrence. We performed RNA-sequencing (RN...

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Detalhes bibliográficos
Main Authors: Gill, Brian J., Pisapia, David J., Malone, Hani R., Goldstein, Hannah, Lei, Liang, Sonabend, Adam, Yun, Jonathan, Samanamud, Jorge, Sims, Jennifer S., Banu, Matei, Dovas, Athanassios, Teich, Andrew F., Sheth, Sameer A., McKhann, Guy M., Sisti, Michael B., Bruce, Jeffrey N., Sims, Peter A., Canoll, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151734/
https://ncbi.nlm.nih.gov/pubmed/25114226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405839111
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