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Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus

In multicellular organisms, specialized functions are delegated to distinct cell types whose identity and functional integrity is maintained upon challenge. However, little is known about the mechanisms enabling lineage inheritance and their biological implications. Regulatory T (Treg) cells, which...

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Détails bibliographiques
Auteurs principaux: Feng, Yongqiang, Arvey, Aaron, Chinen, Takatoshi, van der Veeken, Joris, Gasteiger, Georg, Rudensky, Alexander Y
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151558/
https://ncbi.nlm.nih.gov/pubmed/25126783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.07.031
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