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Control of the inheritance of regulatory T cell identity by a cis element in the Foxp3 locus

In multicellular organisms, specialized functions are delegated to distinct cell types whose identity and functional integrity is maintained upon challenge. However, little is known about the mechanisms enabling lineage inheritance and their biological implications. Regulatory T (Treg) cells, which...

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Autors principals: Feng, Yongqiang, Arvey, Aaron, Chinen, Takatoshi, van der Veeken, Joris, Gasteiger, Georg, Rudensky, Alexander Y
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151558/
https://ncbi.nlm.nih.gov/pubmed/25126783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.07.031
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