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Syntheses and biological evaluation of 2-amino-3-acyl-tetrahydrobenzothiophene derivatives; antibacterial agents with antivirulence activity
Developing new compounds targeting virulence factors (e.g., inhibition of pilus assembly by pilicides) is a promising approach to combating bacterial infection. A high-throughput screening campaign of a library of 17,500 small molecules identified 2-amino-3-acyl-tetrahydrobenzothiophene derivatives...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151345/ https://ncbi.nlm.nih.gov/pubmed/24531242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ob42478b |
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