Development of Carbocyanine Dyes for PRMT Inhibition and Imaging

Protein arginine methylation regulates multiple biological processes. Deregulation of protein arginine methyltransferase (PRMT) activities has been observed in many disease phenotypes. Small molecule probes that target PRMTs with strong affinity and selectivity can be used as valuable tools to disse...

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Detalhes bibliográficos
Main Authors: Sinha, Sarmistha Halder, Owens, Eric A., Feng, You, Yang, Yutao, Xie, Yan, Tu, Yaping, Henary, Maged, Zheng, Yujun George
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151304/
https://ncbi.nlm.nih.gov/pubmed/22749641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2012.06.017
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