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Development of Carbocyanine Dyes for PRMT Inhibition and Imaging
Protein arginine methylation regulates multiple biological processes. Deregulation of protein arginine methyltransferase (PRMT) activities has been observed in many disease phenotypes. Small molecule probes that target PRMTs with strong affinity and selectivity can be used as valuable tools to disse...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151304/ https://ncbi.nlm.nih.gov/pubmed/22749641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2012.06.017 |
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