Development of Carbocyanine Dyes for PRMT Inhibition and Imaging

Protein arginine methylation regulates multiple biological processes. Deregulation of protein arginine methyltransferase (PRMT) activities has been observed in many disease phenotypes. Small molecule probes that target PRMTs with strong affinity and selectivity can be used as valuable tools to disse...

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Main Authors: Sinha, Sarmistha Halder, Owens, Eric A., Feng, You, Yang, Yutao, Xie, Yan, Tu, Yaping, Henary, Maged, Zheng, Yujun George
Format: Artigo
Jezik:Inglês
Izdano: 2012
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151304/
https://ncbi.nlm.nih.gov/pubmed/22749641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2012.06.017
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