Shifting FcγRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis

Rheumatoid arthritis–associated (RA-associated) inflammation is mediated through the interaction between RA IgG immune complexes and IgG Fc receptors on immune cells. Polymorphisms within the gene encoding the human IgG Fc receptor IIA (hFcγRIIA) are associated with an increased risk of developing R...

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Detalhes bibliográficos
Main Authors: Ben Mkaddem, Sanae, Hayem, Gilles, Jönsson, Friederike, Rossato, Elisabetta, Boedec, Erwan, Boussetta, Tarek, El Benna, Jamel, Launay, Pierre, Goujon, Jean-Michel, Benhamou, Marc, Bruhns, Pierre, Monteiro, Renato C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151227/
https://ncbi.nlm.nih.gov/pubmed/25061875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74572
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