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Sexually dimorphic RB inactivation underlies mesenchymal glioblastoma prevalence in males

The prevalence of brain tumors in males is common but unexplained. While sex differences in disease are typically mediated through acute sex hormone actions, sex-specific differences in brain tumor rates are comparable at all ages, suggesting that factors other than sex hormones underlie this discre...

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Detalhes bibliográficos
Main Authors: Sun, Tao, Warrington, Nicole M., Luo, Jingqin, Brooks, Michael D., Dahiya, Sonika, Snyder, Steven C., Sengupta, Rajarshi, Rubin, Joshua B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151215/
https://ncbi.nlm.nih.gov/pubmed/25083989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI71048
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