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CELL INTRINSIC SEXUAL DIMORPHISM IN THE RB AND P21 PATHWAYS UNDERLIES MALE PREDOMINANCE IN GBM

BACKGROUND: Male prevalence across histological subtypes of brain tumors is well known but unexplained. The effects of sex on human disease frequently result from acute actions of circulating sex hormones on cellular physiology and immune function. However, differences in brain tumor rates between m...

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Detalhes bibliográficos
Main Authors: Rubin, Joshua B., Sun, Tao, Warrington, Nicole M., Luo, Jingqin, Brooks, Michael, Dahiya, Sonika, Sengupta, Rajarshi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144536/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.67
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