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CELL INTRINSIC SEXUAL DIMORPHISM IN THE RB AND P21 PATHWAYS UNDERLIES MALE PREDOMINANCE IN GBM

BACKGROUND: Male prevalence across histological subtypes of brain tumors is well known but unexplained. The effects of sex on human disease frequently result from acute actions of circulating sex hormones on cellular physiology and immune function. However, differences in brain tumor rates between m...

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Hlavní autoři: Rubin, Joshua B., Sun, Tao, Warrington, Nicole M., Luo, Jingqin, Brooks, Michael, Dahiya, Sonika, Sengupta, Rajarshi
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4144536/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou206.67
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