Chemical modulation of diphtheria toxin action on cultured mammalian cells.

Ammonium chloride (4 times 10-3 M) rendered HEp-2 monolayers completely insensitive to the action of diphtheria toxin, as measured by de novo protein synthesis. Total protection was observed even with large amounts of toxin (400 minimum lethal doses/ml). Ammonium chloride did not reduce toxicity by...

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Publicat a:Infect Immun
Autors principals: Ivins, B, Saelinger, C B, Bonventre, P F, Woscinski, C
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 1975
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC415119/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/235491/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.11.4.665-674.1975
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