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Chemical modulation of diphtheria toxin action on cultured mammalian cells.

Ammonium chloride (4 times 10-3 M) rendered HEp-2 monolayers completely insensitive to the action of diphtheria toxin, as measured by de novo protein synthesis. Total protection was observed even with large amounts of toxin (400 minimum lethal doses/ml). Ammonium chloride did not reduce toxicity by...

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Detalhes bibliográficos
Main Authors: Ivins, B, Saelinger, C B, Bonventre, P F, Woscinski, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1975
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC415119/
https://ncbi.nlm.nih.gov/pubmed/235491
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