Cofilin recruits F-actin to SPCA1 and promotes Ca(2+)-mediated secretory cargo sorting

The actin filament severing protein cofilin-1 (CFL-1) is required for actin and P-type ATPase secretory pathway calcium ATPase (SPCA)-dependent sorting of secretory proteins at the trans-Golgi network (TGN). How these proteins interact and activate the pump to facilitate cargo sorting, however, is n...

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Bibliographic Details
Main Authors: Kienzle, Christine, Basnet, Nirakar, Crevenna, Alvaro H., Beck, Gisela, Habermann, Bianca, Mizuno, Naoko, von Blume, Julia
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2014
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151145/
https://ncbi.nlm.nih.gov/pubmed/25179631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201311052
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