Presymptomatic Identification of CDH1 Germline Mutation in a Healthy Korean Individual with Family History of Gastric Cancer

Gastric cancer (GC) is one of the most common cancers with high morbidity and mortality. Familial GC is seen in 10% of cases, and approximately 3% of familial GC cases arise owing to hereditary diffuse gastric cancer (HDGC). CDH1, which encodes the protein E-cadherin, is the only gene whose mutation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Choi, Hyun-Jung, Ki, Chang-Seok, Suh, Soon-Pal, Kim, Jong-Won
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Society for Laboratory Medicine 2014
Schlagworte:
Brief Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151009/
https://ncbi.nlm.nih.gov/pubmed/25187893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3343/alm.2014.34.5.386
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