Identification and Characterization of CDH1 Germline Variants in Sporadic Gastric Cancer Patients and in Individuals at Risk of Gastric Cancer

OBJECTIVE: To screen and characterize germline variants for E-cadherin (CDH1) in non-hereditary gastric cancer (GC) patients and in subjects at risk of GC. METHODS: 59 GCs, 59 first degree relatives (FDRs) of GC, 20 autoimmune metaplastic atrophic gastritis (AMAGs) and 52 blood donors (BDs) were ana...

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Hauptverfasser: Garziera, Marica, Canzonieri, Vincenzo, Cannizzaro, Renato, Geremia, Silvano, Caggiari, Laura, De Zorzi, Mariangela, Maiero, Stefania, Orzes, Enrico, Perin, Tiziana, Zanussi, Stefania, De Paoli, Paolo, De Re, Valli
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3812172/
https://ncbi.nlm.nih.gov/pubmed/24204729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077035
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