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Long-term α(1B)-adrenergic receptor activation shortens lifespan, while α(1A)-adrenergic receptor stimulation prolongs lifespan in association with decreased cancer incidence
The α(1)-adrenergic receptor (α(1)AR) subtypes, α(1A)AR and α(1B)AR, have differential effects in the heart and central nervous system. Long-term stimulation of the α(1A)AR subtype prolongs lifespan and provides cardio- and neuro-protective effects. We examined the lifespan of constitutively active...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4150908/ https://ncbi.nlm.nih.gov/pubmed/24994537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-014-9675-7 |
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