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Long-term α(1B)-adrenergic receptor activation shortens lifespan, while α(1A)-adrenergic receptor stimulation prolongs lifespan in association with decreased cancer incidence

The α(1)-adrenergic receptor (α(1)AR) subtypes, α(1A)AR and α(1B)AR, have differential effects in the heart and central nervous system. Long-term stimulation of the α(1A)AR subtype prolongs lifespan and provides cardio- and neuro-protective effects. We examined the lifespan of constitutively active...

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Hlavní autoři: Collette, Katie M., Zhou, Xu Dong, Amoth, Haley M., Lyons, Mariaha J., Papay, Robert S., Sens, Donald A., Perez, Dianne M., Doze, Van A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150908/
https://ncbi.nlm.nih.gov/pubmed/24994537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-014-9675-7
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