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Effect of growth hormone receptor gene disruption and PMA treatment on the expression of genes involved in primordial follicle activation in mice ovaries

The activation of the Pi3k-Akt1-FOXO pathway seems to be involved in the extended longevity observed in growth hormone receptor/growth hormone binding protein knockout (GHRKO) mice and is related to the growth of primordial ovarian follicles. The aim of this work was to measure the expression of gen...

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Main Authors: Schneider, Augusto, Zhi, Xu, Bartke, Andrzej, Kopchick, John J., Masternak, Michal M.
Formato: Artigo
Idioma:Inglês
Publicado: Springer Netherlands 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150892/
https://ncbi.nlm.nih.gov/pubmed/25099774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-014-9701-9
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