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T Cell Avidity and Tumor Immunity: Problems and Solutions

A potent T cell response is an important component of durable anti-tumor immunity. The quality of the T cell response can, in-part, be measured by the avidity of the T cell for its tumor antigen-expressing target. While convention suggests that raising the avidity of the responding T cells may make...

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Autori principali: Hurwitz, Arthur A., Cuss, Steven M., Stagliano, Katherine E., Zhu, Ziqiang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150879/
https://ncbi.nlm.nih.gov/pubmed/24357332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12307-013-0143-1
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