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MC1R, the cAMP pathway and the response to solar UV: Extending the horizon beyond pigmentation

The melanocortin 1 receptor (MC1R) is a G protein-coupled receptor crucial for the regulation of melanocyte proliferation and function. Upon binding melanocortins, MC1R activates several signaling cascades, notably the cAMP pathway leading to synthesis of photoprotective eumelanin. Polymorphisms in...

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Bibliografski detalji
Glavni autori: García-Borrón, Jose C, Abdel-Malek, Zalfa, Jiménez-Cervantes, Celia
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150834/
https://ncbi.nlm.nih.gov/pubmed/24807163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12257
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