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MC1R, the cAMP pathway and the response to solar UV: Extending the horizon beyond pigmentation
The melanocortin 1 receptor (MC1R) is a G protein-coupled receptor crucial for the regulation of melanocyte proliferation and function. Upon binding melanocortins, MC1R activates several signaling cascades, notably the cAMP pathway leading to synthesis of photoprotective eumelanin. Polymorphisms in...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4150834/ https://ncbi.nlm.nih.gov/pubmed/24807163 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12257 |
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