Effects of genetic variations on microRNA: target interactions

Genetic variations within microRNA (miRNA) binding sites can affect miRNA-mediated gene regulation, which may lead to phenotypes and diseases. We perform a transcriptome-scale analysis of genetic variants and miRNA:target interactions identified by CLASH. This analysis reveals that rare variants ten...

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Autori principali: Liu, Chaochun, Rennie, William A., Carmack, C. Steven, Kanoria, Shaveta, Cheng, Jijun, Lu, Jun, Ding, Ye
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2014
Soggetti:
Computational Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150780/
https://ncbi.nlm.nih.gov/pubmed/25081214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku675
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