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SpliceNet: recovering splicing isoform-specific differential gene networks from RNA-Seq data of normal and diseased samples

Conventionally, overall gene expressions from microarrays are used to infer gene networks, but it is challenging to account splicing isoforms. High-throughput RNA Sequencing has made splice variant profiling practical. However, its true merit in quantifying splicing isoforms and isoform-specific exo...

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Hlavní autoři: Yalamanchili, Hari Krishna, Li, Zhaoyuan, Wang, Panwen, Wong, Maria P., Yao, Jianfeng, Wang, Junwen
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150760/
https://ncbi.nlm.nih.gov/pubmed/25034693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku577
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