Genome-wide mapping of unexplored essential regions in the Saccharomyces cerevisiae genome: evidence for hidden synthetic lethal combinations in a genetic interaction network

Despite systematic approaches to mapping networks of genetic interactions in Saccharomyces cerevisiae, exploration of genetic interactions on a genome-wide scale has been limited. The S. cerevisiae haploid genome has 110 regions that are longer than 10 kb but harbor only non-essential genes. Here, w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kaboli, Saeed, Yamakawa, Takuya, Sunada, Keisuke, Takagaki, Tao, Sasano, Yu, Sugiyama, Minetaka, Kaneko, Yoshinobu, Harashima, Satoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2014
Schlagworte:
Genomics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150759/
https://ncbi.nlm.nih.gov/pubmed/25104020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku576
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