Enhancing immunomodulation on innate immunity by shape transition among RNA triangle, square and pentagon nanovehicles

Modulation of immune response is important in cancer immunotherapy, vaccine adjuvant development and inflammatory or immune disease therapy. Here we report the development of new immunomodulators via control of shape transition among RNA triangle, square and pentagon. Changing one RNA strand in poly...

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Détails bibliographiques
Auteurs principaux: Khisamutdinov, Emil F., Li, Hui, Jasinski, Daniel L., Chen, Jiao, Fu, Jian, Guo, Peixuan
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2014
Sujets:
RNA
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150753/
https://ncbi.nlm.nih.gov/pubmed/25092921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku516
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