Loss of Vhl in cartilage accelerated the progression of age-associated and surgically induced murine osteoarthritis

OBJECTIVE: To investigate the role of Vhl in maintaining the integrity of articular cartilage and in the development of experimental osteoarthritis (OA). METHOD: Histology of articular cartilage and subchondral bone in both Vhl cKO and WT mice were analyzed by histopathology and micro-CT. Articular...

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Detalhes bibliográficos
Main Authors: Weng, Tujun, Xie, Yangli, Yi, Lingxian, Huang, Junlan, Luo, Fengtao, Du, Xiaolan, Chen, Liang, Liu, Chongyang, Chen, Di, Chen, Lin
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150692/
https://ncbi.nlm.nih.gov/pubmed/24999110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.joca.2014.06.031
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