Insights into DNA hydroxymethylation in the honeybee from in-depth analyses of TET dioxygenase

In mammals, a family of TET enzymes producing oxidized forms of 5-methylcytosine (5mC) plays an important role in modulating DNA demethylation dynamics. In contrast, nothing is known about the function of a single TET orthologue present in invertebrates. Here, we show that the honeybee TET (AmTET) c...

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Bibliographic Details
Main Authors: Wojciechowski, Marek, Rafalski, Dominik, Kucharski, Robert, Misztal, Katarzyna, Maleszka, Joanna, Bochtler, Matthias, Maleszka, Ryszard
Format: Artigo
Language:Inglês
Published: The Royal Society 2014
Subjects:
Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150289/
https://ncbi.nlm.nih.gov/pubmed/25100549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.140110
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