Selective CREB-dependent cyclin expression mediated by the PI3K and MAPK pathways supports glioma cell proliferation

The cyclic-AMP response element binding (CREB) protein has been shown to have a pivotal role in cell survival and cell proliferation. Transgenic rodent models have revealed a role for CREB in higher-order brain functions, such as memory and drug addiction behaviors. CREB overexpression in transgenic...

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Detalhes bibliográficos
Main Authors: Daniel, P, Filiz, G, Brown, D V, Hollande, F, Gonzales, M, D'Abaco, G, Papalexis, N, Phillips, W A, Malaterre, J, Ramsay, R G, Mantamadiotis, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4150215/
https://ncbi.nlm.nih.gov/pubmed/24979279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2014.21
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