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Angiotensin II has acute effects on TRPC6 channels in podocytes of freshly isolated glomeruli

A key role for podocytes in the pathogenesis of proteinuric renal diseases has been established. Angiotensin II causes depolarization and increased intracellular calcium concentration in podocytes; members of the cation TRPC channels family, particularly TRPC6, are proposed as proteins responsible f...

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Hlavní autoři: Ilatovskaya, Daria V., Palygin, Oleg, Chubinskiy-Nadezhdin, Vladislav, Negulyaev, Yuri A., Ma, Rong, Birnbaumer, Lutz, Staruschenko, Alexander
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149864/
https://ncbi.nlm.nih.gov/pubmed/24646854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2014.71
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