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Podocyte injury in diabetic nephropathy: implications of angiotensin II – dependent activation of TRPC channels
Injury to podocytes is considered a major contributor to diabetic kidney disease: their loss causes proteinuria and progressive glomerulosclerosis. Podocyte depletion may result from improper calcium handling due to abnormal activation of the calcium permeant TRPC (Transient Receptor Potential Canon...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4674698/ https://ncbi.nlm.nih.gov/pubmed/26656101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17637 |
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