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Podocyte injury in diabetic nephropathy: implications of angiotensin II – dependent activation of TRPC channels

Injury to podocytes is considered a major contributor to diabetic kidney disease: their loss causes proteinuria and progressive glomerulosclerosis. Podocyte depletion may result from improper calcium handling due to abnormal activation of the calcium permeant TRPC (Transient Receptor Potential Canon...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Ilatovskaya, Daria V., Levchenko, Vladislav, Lowing, Andrea, Shuyskiy, Leonid S., Palygin, Oleg, Staruschenko, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674698/
https://ncbi.nlm.nih.gov/pubmed/26656101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17637
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