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Absence of a simple code: how transcription factors read the genome

Transcription factors (TFs) influence cell fate by interpreting the regulatory DNA within a genome. TFs recognize DNA in a specific manner; the mechanisms underlying this specificity have been identified for many TFs, based on three-dimensional structures of protein-DNA complexes. More recently, str...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Slattery, Matthew, Zhou, Tianyin, Yang, Lin, Machado, Ana Carolina Dantas, Gordân, Raluca, Rohs, Remo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149858/
https://ncbi.nlm.nih.gov/pubmed/25129887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2014.07.002
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